KH 176

CAS No. 2162149-24-6

KH 176 ( KH176 )

Catalog No. M13449 CAS No. 2162149-24-6

KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 358 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    KH 176
  • Note
    Research use only, not for human use.
  • Brief Description
    KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator.
  • Description
    KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders; retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex, significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice.Other Indication Phase 2 Clinical
  • Synonyms
    KH176
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    2162149-24-6
  • Formula Weight
    368.90
  • Molecular Formula
    C19H29ClN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (S)-6-hydroxy-2,5,7,8-tetramethyl-N-((R)-piperidin-3-yl)chroman-2-carboxamide hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. de Haas R, et al. Sci Rep. 2017 Sep 15;7(1):11733.
2. Koene S, et al. Orphanet J Rare Dis. 2017 Oct 16;12(1):163.
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