KH 176
CAS No. 2162149-24-6
KH 176 ( KH176 )
Catalog No. M13449 CAS No. 2162149-24-6
KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 358 | Get Quote |
|
50MG | 1782 | Get Quote |
|
100MG | 2250 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameKH 176
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NoteResearch use only, not for human use.
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Brief DescriptionKH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator.
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DescriptionKH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders; retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex, significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice.Other Indication Phase 2 Clinical
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SynonymsKH176
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number2162149-24-6
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Formula Weight368.90
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Molecular FormulaC19H29ClN2O3
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(S)-6-hydroxy-2,5,7,8-tetramethyl-N-((R)-piperidin-3-yl)chroman-2-carboxamide hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. de Haas R, et al. Sci Rep. 2017 Sep 15;7(1):11733.
2. Koene S, et al. Orphanet J Rare Dis. 2017 Oct 16;12(1):163.
2. Koene S, et al. Orphanet J Rare Dis. 2017 Oct 16;12(1):163.
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